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What is Oxymetholone?
Buy Oxymetholone 50mg online Oxymetholone is an anabolic steroid, which is a man-made form of a hormone similar to testosterone.
This medication is a synthetic male hormone (androgen or anabolic steroid) used to treat a low red blood cell count (anemia). It works by increasing the amount of the hormone (erythropoietin) involved in the production of red blood cells.
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DOSAGE & INDICATIONS
For the treatment of anemia caused by deficient red cell production, including aplastic anemia (acquired and congenital), myelofibrosis, and hypoplastic anemia due to myelotoxic drugs.
Children, Adolescents, and Adults
1—2 mg/kg/day orally is the usual effective dosage in children and adults; however, oxymetholone therapy should be individualized and a higher dosage may be necessary (up to 5 mg/kg/day). Because response may be delayed, a minimum of 3—6 months of therapy is recommended. Once remission is achieved, therapy may be discontinued or decreased in some patients. Patients with congenital aplastic anemia usually require maintenance therapy.
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For the treatment of AIDS-associated wasting syndrome†.
50 mg orally twice daily for up to 32 weeks resulted in a 5.3% increase in total weight gain from baseline in patients with HIV and weight loss in a randomized, double-blind, placebo-controlled, phase III study. Eugonadal HIV patients (male, n = 79; female, n = 10) who were receiving highly active antiretroviral therapy for more than 3 months and had experienced a weight loss of at least 5% in the previous 6 months or were 10% below ideal body weight in the previous 12 months were randomized to receive treatment with oxymetholone 50 mg twice daily (n = 30) or oxymetholone 50 mg 3 times daily (n = 31) or matching placebo given 2 or 3 times daily (n = 28) for 16 weeks; 72 of these patients then received an additional 16 weeks of oxymetholone 50 mg twice daily in an open-label maintenance phase. In patients who received oxymetholone therapy,the onset of weight gain started within 4 weeks and resulted in a total weight gain of up to 3.5 kg (twice daily dosing, 3.5 +/- 0.7 kg; 3 times daily dosing, 3 +/- 0.5 kg; placebo, 1 +/- 0.7 kg). Additionally, lean body mass was increased by 2.9 +/- 0.54 kg with twice daily oxymetholone compared with 1.8 +/- 0.8 kg with 3 times daily oxymetholone dosing (p < 0.0001). Serious liver related side effects were reported with oxymetholone therapy including elevated liver enzymes, jaundice, hepatomegaly, and hyperbilirubinemia.
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